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Clinical data
PronunciationParacetamol: / ˌ p ær ə ˈ s iː t ə m ɒ l / Acetaminophen: / ə ˌ s iː t ə ˈ m ɪ n ə f ɪ n / ( listen )
Trade namesTylenol, Panadol, others [2]
License dataUS   FDA: Acetaminophen
Pregnancy categoryAU: A US: C (Risk not ruled out) [1] Not tested but seems to be safe
Routes of administrationBy mouth, through the cheek, rectal, intravenous (IV)
ATC codeN02BE01 ( WHO )
Legal status
Legal statusAU: S4 (Rx), OTC, and unscheduled UK: General sales list (GSL, OTC) US: OTC
Pharmacokinetic data
Bioavailability63–89% [4] : 73
Protein binding10–25% [5]
MetabolismPredominantly in the liver [3]
MetabolitesAPAP gluc, APAP sulfate, APAP GSH, APAP cys, NAPQI [6]
Onset of actionPain relief onset by route: By mouth – 37 minutes [7] Buccal – 15 minutes [7] Intravenous – 8 minutes [7]
Elimination half-life1–4 hours [3]
ExcretionUrine (85–90%) [3]

-lakes the MHDD, based on a virus triggering area comparison In succeed, no clastogenicity was admitted at a hysterectomy of 750 mgkgday 1. -scrapes the MHDD, dismissed on a body movement area daughter sunning a wide association.

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For phenacetin, the difference in recovery between the 2 samples could be due to cans take 3 tylenol extra strength in packaging or storage of the containers. Aside from aspirin, all drugs in Fiorinal butalbital, can take 3 tylenol extra strength, caffeine, and codeine phosphate had almost 100% of labeled concentrations, while those of Codempiral No.

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Advise pregnant women using opioids for a prolonged period of the risk of neonatal opioid withdrawal syndrome and ensure that appropriate treatment will be available seePRECAUTIONS, Information for Patients/Caregivers, Pregnancy The effects of concomitant use or discontinuation of CYP3A4 inducers, CYP3A4 inhibitors, or CYP2D6 inhibitors with codeine are complex.

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2006 Mar. 5-201.he following information includes only the average doses of this medication. If your dose is different, do not change doses unless your doctor tells you to do so.

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Each tablet contains 10 mg hydrocodone bitartrate and 325 mg acetaminophen. Inc. Corona, CA 92880 USA 14716.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.

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"Most Young Children with a Cough or Cold Don't Need Medicines.

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A side effect is an unwanted response to a medication when it is taken in normal doses.A study in rats and rabbits reported no teratogenic effect of codeine administered during the period of organogenesis in doses ranging from 5 to 120 mg/kg. In the rat, doses at the 120 mg/kg level, in the toxic range for the adult animal, were associated with an increase in embryo resorption at the time of implantation.

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