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|Pronunciation||Paracetamol: / ˌ p ær ə ˈ s iː t ə m ɒ l / Acetaminophen: / ə ˌ s iː t ə ˈ m ɪ n ə f ɪ n / ( listen )|
|Trade names||Tylenol, Panadol, others |
|License data||US FDA: Acetaminophen|
|Pregnancy category||AU: A US: C (Risk not ruled out)  Not tested but seems to be safe|
|Routes of administration||By mouth, through the cheek, rectal, intravenous (IV)|
|ATC code||N02BE01 ( WHO )|
|Legal status||AU: S4 (Rx), OTC, and unscheduled UK: General sales list (GSL, OTC) US: OTC|
|Bioavailability||63–89%  : 73|
|Protein binding||10–25% |
|Metabolism||Predominantly in the liver |
|Metabolites||APAP gluc, APAP sulfate, APAP GSH, APAP cys, NAPQI |
|Onset of action||Pain relief onset by route: By mouth – 37 minutes  Buccal – 15 minutes  Intravenous – 8 minutes |
|Elimination half-life||1–4 hours |
|Excretion||Urine (85–90%) |
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2006 Mar. 5-201.he following information includes only the average doses of this medication. If your dose is different, do not change doses unless your doctor tells you to do so.
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Each tablet contains 10 mg hydrocodone bitartrate and 325 mg acetaminophen. Inc. Corona, CA 92880 USA 14716.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
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Buprenorphine Physical dependence may not occur to a clinically significant degree until after several days to weeks of continued opioid usage.The safety of giving infants and children over-the-counter OTC cold and cough medicine is important for caregivers to understand. While there is no gold standard recommendation for giving infants and children OTC cold and cough medicine for fever, aches, cough, and runny nose, a few standards have The American College of Chest Physicians recommend that these medicines only The FDA recommends that OTC how much tylenol does it take to od and cough medicine be used in children 2 However, how much tylenol does it take to od is agreement in regard to which OTC medications should not be used in children under the age of four or the age of two, depending upon which guidelines are used and they are 1 certain antihistamines like brompheniramine, chlorpheniramine maleate, and diphenhydramine Benadryl 2 cough expectorants guaifenesin 3 cough suppressants dextromethorphan, DM and 4 decongestants pseudoephedrine and phenylephrine Aspirin should never be given to infants, children, and adolescents due to the possibility of a rare, but often severe and even fatal illness called Reye s REFERENCES: DA.
"Most Young Children with a Cough or Cold Don't Need Medicines.
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A side effect is an unwanted response to a medication when it is taken in normal doses.A study in rats and rabbits reported no teratogenic effect of codeine administered during the period of organogenesis in doses ranging from 5 to 120 mg/kg. In the rat, doses at the 120 mg/kg level, in the toxic range for the adult animal, were associated with an increase in embryo resorption at the time of implantation.
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Medline. Rumack BH. Acetaminophen overdose.Be sure you know how to take hydrocodone/acetaminophen and what other drugs you should avoid taking with it.
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