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Diphenhydramine
Clinical data
Pronunciation/ ˌ d aɪ f ɛ n ˈ h aɪ d r ə m iː n /
Trade namesBenadryl, Unisom, Sominex, others
AHFS/Drugs.comMonograph
MedlinePlusa682539
Pregnancy categoryAU: A US: B (No risk in non-human studies)
Dependence liabilityVery low
Routes of administrationBy mouth, intramuscular injection, intravenous, topical, rectal
ATC codeD04AA32 ( WHO ) D04AA33 ( WHO ), R06AA02 ( WHO )
Legal status
Legal statusAU: S2 (Pharmacy only) US: OTC
Pharmacokinetic data
Bioavailability40–60% [2]
Protein binding98–99%
MetabolismLiver (CYP2D6 (80%), CYP3A4 (10%)) [1]
Elimination half-lifeRange: 2.4–13.5 hrs [3] [2] [4]
ExcretionUrine: 94% [5] Feces: 6% [5]

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Register now at no benadryl dosage for anxiety to access unlimited clinical news with personalized daily picks for you, full-length features, case studies, conference coverage, and more.An antihistamine pill, such as diphenhydramine Benadryl isn't sufficient to treat anaphylaxis.

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Its drying effects on such symptoms as watery eyes and runny nose are caused by blocking another natural substance made by your body acetylcholine Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years.Seek emergency medical attention or call the Poison Help line at.

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Revision date.Your tax-deductible gift will help fund vital research leading to better treatments, finding an RLS cure and improving the lives of those living with RLS. We could use your help! From Awareness Day, to online events, to local support group leaders, and more.

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This material is provided for benadryl calm anxiety purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex updated 10 Aug 2020 Cerner Multum updated 3 Aug 2020 Wolters Kluwer updated 10 Aug 2020 andothers.Newer antihistamines benadryl calm anxiety fexofenadine Allegra and loratidine Claritin have not been shown to work for cold symptoms. A decongestant called phenylpropanolamine PPA was used for years as an ingredient in many cold drugs to clear up a stuffy nose.

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