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8. Phenoxymethylpenicillin J01CE02. 9. Flucloxacillin J01CF05. 10. Amoxicillin & Enzyme Inhibitor J01CR02. 11. Cefalexin J01DB01. 12. Cefuroxime J01DC02.

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Cefuroxime
Clinical data
Trade namesZinacef, Ceftin, others
AHFS/Drugs.comMonograph
MedlinePlusa601206
Pregnancy categoryB
Routes of administrationIntramuscular, intravenous, by mouth
Drug classSecond-generation cephalosporin
ATC codeJ01DC02 ( WHO ) S01AA27 ( WHO ) QJ51DC02 ( WHO )
Legal status
Legal statusIn general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability37% on an empty stomach, up to 52% if taken after food
Elimination half-life80 minutes
ExcretionUrine 66–100% unchanged

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Owder for Oral Suspension: 125 or 250 mg per 5 ml teaspoon Injection: 750 mg, 1.This minimized disproportional allocation of high-risk patients into one treatment regimen. The study patients were monitored daily by the clinical investigators at each participating site, and the decision to switch to oral therapy was made on the basis of improvement in cough, diminution in purulent sputum production, defervescence, and reduction in leukocytosis.

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During clinical trials, discontinuation of therapy due to the taste and/or problems with administering this cefuroxime axetil tablet ip 500 occurred in.The following were routinely ordered for each study patient: a sputum specimen for culture and Gram stain; 2 sets of blood cultures; specialized testing for Legionella species, including culture of sputum on selective media, 0 direct fluorescent antibody stains monoclonal and polyclonal urinary antigen, serological studies IgG and IgM for L pneumophila serogroups 1 through 6 and Legionella micdadei at baseline acute at time of hospital discharge, and again at 4- to 6-week posttreatment cefuroxime axetil tablet ip 500 visits; serological studies for antibody against C pneumoniae and M pneumoniae at baseline, at time of hospital discharge, and again at 4- to 6-week posttreatment follow-up visits by microimmunofluorescence and complement-fixation methods; polymerase chain reaction assays of oropharyngeal swab specimens for detection of L pneumophila, C pneumoniae, and M pneumoniae11; and culture of pleural fluid or bronchoalveolar lavage when available.

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Several cephalosporins, including ZINACEF, have been implicated in triggering seizures, particularly in patients with renal impairment when the dosage was not reduced see DOSAGE AND ADMINISTRATION If seizures associated with drug therapy should occur, the drug should be discontinued.

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Ov/STIC. Although lifetime studies in animals have not been performed to evaluate carcinogenic potential, no mutagenic activity was found for cefuroxime axetil in a battery of bacterial mutation tests.Dosage adjustment is required for patients with impaired renal function.

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Allergy cefuroxime axetil tablet should be considered in any patient with recurrent acute or cefuroxime axetil tablet sinusitis to rule out allergy as a contributing factor for sinusitis.Cefuroxime has in vitro activity against a wide range of gram-positive and gram-negative organisms, and it is highly stable in the presence of beta-lactamases of certain gram-negative bacteria. The bactericidal action of cefuroxime results from inhibition of cell-wall synthesis.

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2nd ed. Philadelphia: W B Saunders Co. 5-1069.g/1IntravenousFresenius Kabi USA, LLC2011-05-242014-04-17USCefuroximeInjection, powder, for solution1.

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