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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Cyclosporine (neoral) pack 100 mg 10 the amount of packaging.

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Ciclosporin
Clinical data
Pronunciation/ ˌ s aɪ k l ə ˈ s p ɔːr ɪ n / [2]
Trade namesNeoral, Sandimmune, others
AHFS/Drugs.comMonograph
MedlinePlusa601207
License dataEU  EMA:  by INN
Pregnancy categoryAU: C US: C (Risk not ruled out)
Routes of administrationBy mouth, IV, eye drops
Drug classimmunosuppressant calcineurin inhibitor eye medication
ATC codeL04AD01 ( WHO ) S01XA18 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
BioavailabilityVariable
Metabolismliver CYP3A4
Elimination half-lifeVariable (about 24 hours)
Excretionbiliary
Ciclosporin

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Copyright 2020 IBM Watson Health.In this population the cyclosporine blood trough concentration should be generic for neoral more frequently, at least twice a week daily, if initial dose exceeds 10 mg/kg/day until the concentration stabilizes within the desired range.

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