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Tell your doctor or pharmacist if you are taking other products that cause drowsiness including alcohol, marijuana (cannabis) antihistamines (such as cetirizine, diphenhydramine) drugs for sleep or anxiety (such as alprazolam, zolpidem) muscle relaxants (such as carisoprodol, cyclobenzaprine) and opioid pain relievers (such as codeine, hydrocodone) Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Depakote (divalproex) pack 125 mg 120 quantity in a package.

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Valproate
Clinical data
Trade namesConvulex, Depakote, Epilim, Stavzor, and others
AHFS/Drugs.comMonograph
MedlinePlusa682412
Pregnancy categoryAU: D US: X (Contraindicated) - only for epilepsy or bipolar if other options are not possible [1]
Routes of administrationBy mouth, intravenous
ATC codeN03AG01 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
BioavailabilityRapid absorption
Protein binding80–90% [2]
MetabolismHepatic—glucuronide conjugation 30–50%, mitochondrial β-oxidation over 40%
Elimination half-life9–16 hours [2]
ExcretionUrine (30-50%) [2]
Sodium valproate

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Topamax depakote clearance may be decreased in special patient populations e. patients with renal failure, geriatric patients Because hemodialysis typically reduces plasma valproic acid concentration by about 20% generally there is no dosage adjustment required in patients with renal failure i.You may report side effects topamax depakote FDA at 1-800-FDA-1088.

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Initially, phenobarbital topamax and depakote cause drowsiness, but the child usually develops tolerance to this side effect. Side effects: After several weeks or months of treatment, some children may develop hyperactivity, aggression, and insomnia.Keep DEPAKOTE and all other medications where children cannot reach them. If you have any questions about AbbVie's Depakote.

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This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex updated 10 Aug 2020 Cerner Multum updated 3 Aug 2020 Wolters Kluwer updated 10 Aug 2020 andothers.10: CD003945. doi.

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In the review, researchers first depakote and topamax took together at eight studies that included nearly 1, 00 births and identified some 14 birth defects that seemed to be much more common among the children of women who took valproic acid early in pregnancy.An Annual Risk Acknowledgement Form needs to be used at time of treatment initiation and during each annual review of valproate treatment by the specialist.

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I depakote topamax take Ambien and citolopram. I feel like that s a lot of chemicals in my body.Cholestyramine may lead to a decrease in plasma level of valproate when co-administered.

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