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Doxepin
Clinical data
Trade namesSinequan, Quitaxon, Aponal, others [2]
AHFS/Drugs.comMonograph
MedlinePlusa682390
License dataUS   FDA: Doxepin
Pregnancy categoryAU: C US: B (No risk in non-human studies)
Routes of administrationBy mouth, topical, intravenous, intramuscular injection [1]
Drug classTricyclic antidepressant (TCA)
ATC codeD04AX01 ( WHO ) N06AA12 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability13–45% (mean 29%) [5] [6]
Protein binding76% [7]
MetabolismHepatic (CYP2D6, CYP2C19) [4] [5]
MetabolitesNordoxepin, glucuronide conjugates [4]
Elimination half-lifeDoxepin: 8–24 hours (mean 17 hours) [7] Nordoxepin: 31 hours [7]
ExcretionUrine: ~50% [4] [5] Feces: minor [5]
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Doxepin product name goods:
  1. Adapin 10 mg
  2. Anten 10 mg
  3. Aponal 75 mg
  4. Deptran 10 mg
  5. Doneurin 75 mg
  6. Doxal 10 mg
  7. Doxépine 75 mg
  8. Doxepini 10 mg
  9. Doxepinum 10 mg
  10. Doxin 75 mg
  11. Espadox 25 mg
  12. Expan 10 mg
  13. Gilex 75 mg
  14. Ichderm 25 mg
  15. Mareen 10 mg
  16. Quitaxon 10 mg
  17. Sagalon 10 mg
  18. Silenor 75 mg
  19. Sinepin 10 mg
  20. Sinquan 75 mg
  21. Spectra 75 mg
  22. Triadapin 10 mg

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Doxepin about
Tablets name Doxepin
Doxepin other namesadapin, anten, aponal, deptran, doneurin, doxal, doxépine, doxepini, doxepinum, doxin, espadox, expan, gilex, ichderm, mareen, quitaxon, sagalon, silenor, sinepin, sinquan, spectra, triadapin, xepin, zonalon
Active substancessinequan
Best price 60 USD
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    The 150 mg capsule strength is intended for maintenance therapy only and is not recommended for doxepin 3 mg of treatment. Antianxiety effect is apparent before the antidepressant effect.No suicides occurred in any of the pediatric trials.

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