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Therefore, an increase or decrease in the metabolism of CYP3A substrates e. duloxetine hcl enteric coated contraceptives and other steroidal agents resulting from induction or inhibition is not anticipated, although clinical studies have not been performed.Orthostatic Hypotension, Falls and Syncope see Warnings and Precautions 5. Discontinuation of Treatment with duloxetine see Warnings and Precautions 5.

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Also report any duloxetine hcl enteric coated skin changes such as blisters or rashes problems with urination, eye pain or swelling, and vision changes.These studies did not show an increase in the risk of suicidal thoughts and behavior with antidepressant use in patients over age 24; duloxetine hcl enteric coated was a reduction in risk with antidepressant use in patients aged 65 and older see Warnings and Precautions 5.

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It is unknown whether the suicidality risk extends to longer-term use, i. beyond several months.Duloxetine may increase the effects of other medications that can cause bleeding e.

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E-mail address, name, etc. WebMD does not endorse any specific product, service, or treatment.Table 2 gives the incidence of treatment-emergent adverse reactions in placebo-controlled trials for approved indications that occurred in 5% or more of duloxetine indications treated with CYMBALTA and duloxetine indication an incidence greater than placebo.

Table 2: Treatment-Emergent Adverse Reactions: Incidence of 5% or More and Greater than Placebo in Placebo-Controlled Trials of Approved Indicationsa a The duloxetine indication of an event in the table is determined based on the percentages before rounding; however, the percentages displayed in the table are rounded to the nearest integer.

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To 6.The efficacy of Duloxetine Delayed-release Capsules in duloxetine indication low duloxetine indication pain CLBP was assessed in two double-blind, placebo-controlled, randomized clinical trials of 13-weeks duloxetine indication Study CLBP-1 and Study CLBP-2 and one of 12-weeks duration CLBP-3 CLBP-1 and CLBP-3 demonstrated efficacy of Duloxetine Delayed-release Capsules in the treatment of chronic low back pain. Patients in all studies had no signs of radiculopathy or spinal stenosis.

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