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2 Insulin glargine was approved for medical use in the United States in 2000. 2 In 2017, it was the 33rd most commonly prescribed diabetes drug lantus in the United States diabetes drug lantus more than 20 million prescriptions.Repeated insulin injections into areas of lipodystrophy or localized cutaneous amyloidosis may result in hyperglycemia; sudden change in the injection site to unaffected area has been reported to result in hypoglycemia.
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