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octreotide and sulfonamide antibiotics. Get to know the Lantus® SoloSTAR® pen page. Lantus website. Available at: http://www.lantus.com/considering/ lantus-solostar -features/know- ... Positive evidence of human fetal risk.

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Units/kg/day during growth spurts Dosage of human insulin, which is always expressed in USP units, must be based on the results of blood and urine glucose tests and must be carefully individualized to optimal effect If changing from a treatment regimen with an intermediate- or a long-acting insulin to a regimen with insulin glargine, the amount and timing of shorter-acting insulins and doses of any oral antidiabetic drugs may need to be adjusted If changing from once-daily NPH insulin to once-daily insulin glargine: Initial dose is the same as the dose of NPH that is being discontinued If changing lantus solostar efectos secundarios twice-daily NPH insulin to once-daily insulin glargine: Initial dose is 80% of the total daily NPH dose that is being discontinued; this dose reduction will lower the likelihood of hypoglycemiaHeadache Influenza-like symptoms Dyspepsia Diarrhea Back pain Pharyngitis Lipodystrophy Lipohypertrophy Pallor Palpitation Tachycardia Local allergic reaction Hypokalemia Peripheral edema Localized cutaneous amyloidosis Documented hypersensitivity During episodes of hypoglycemia Toujeo and Lantus are not interchangeable Not recommended for treating diabetic ketoacidosis; use IV short-acting insulin lantus solostar efectos secundarios Never share insulin pens between patients, even if the needle is changed; pen sharing poses a risk for transmission of blood-borne pathogens To avoid dosing lantus solostar efectos secundarios and potential overdose, never use a syringe to remove drug from TOUJEO SoloStar or TOUJEO Max SoloStar prefilled pen into a syringe Decreased insulin requirements: Diarrhea, nausea/vomiting, malabsorption, hypothyroidism, renal impairment, hepatic impairment Increased insulin requirements include fever, hyperthyroidism, trauma, infection, surgery Increase frequency of glucose monitoring with changes to insulin dosage, coadministered glucose lowering medications, meal pattern, or physical activity; and in patients with renal or hepatic impairment and hypoglycemia unawareness Accidental mix-ups between insulin products can occur; instruct patients to check insulin labels before injection Rapid changes in serum glucose may induce symptoms of hypoglycemia Hypoglycemia is the most common cause of adverse reactions eg, headache, tachycardia May cause a shift in potassium from extracellular to intracellular space, possibly leading to hypokalemia; caution when coadministered lantus solostar efectos secundarios potassium-lowering drugs or conditions that may decrease potassium Frequent glucose monitoring and insulin dose reduction may be required with renal or hepatic impairment; not recommended during periods of rapidly declining renal or hepatic function because of risk for prolonged hypoglycemia Use caution during pregnancy Changes in insulin, insulin lantus solostar efectos secundarios, manufacturer, type, or method of administration may affect glycemic control and predispose to hypoglycemia or hyperglycemia Changes should be made cautiously and only under close medical supervision and frequency of blood glucose monitoring should be increased Repeated insulin injections into areas of lipodystrophy or localized cutaneous amyloidosis reported to result in lantus solostar efectos secundarios a sudden change in the injection site to unaffected area has been reported to result in hypoglycemia Make any changes to a patient s insulin regimen under close medical supervision with increased frequency of blood glucose monitoring Lantus solostar efectos secundarios patients who have repeatedly injected into areas of lipodystrophy or localized lantus solostar efectos secundarios amyloidosis to change injection site to unaffected areas and closely monitor for hypoglycemia For patients with type 2 diabetes, dosage adjustments in concomitant oral antidiabetic treatment may be needed The FDA reviewed 4 published observational studies, 3 of which suggested an increased risk of cancer lantus solostar efectos secundarios with insulin glargine It was determined that the evidence presented in these studies is inconclusive due to methodologic limitations The duration of patient follow-up in all 4 studies was shorter than that which is generally considered necessary to lantus solostar efectos secundarios cancer risk from drug exposure Also, the 4 studies provided limited information on patients use of insulin products; some studies did not take into account whether the patients used any antidiabetic drugs before the study time period or whether there were any changes in how patients used these drugs during the study period Furthermore, risk factors for cancer eg, smoking, family history of cancer, obesity may not have been adequately controlled for in these studies Thiazolidinediones are peroxisome proliferator-activated receptor PPAR gamma agonists and can cause dose-related fluid retention, particularly when used in combination with insulin; lantus solostar efectos secundarios retention may lead to or exacerbate heart failure; monitor for signs and symptoms of heart failure, treat accordingly, and consider discontinuing thiazolidinediones Coadministration with these drugs eg, antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine lantus solostar efectos secundarios inhibitors, pentoxifylline, pramlintide, propoxyphene, salicylates, somatostatin analogseg, octreotide, sulfonamide antibiotics, GLP-1 receptor agonists, DPP-4 inhibitors, and SGLT-2 inhibitors may increase the risk of hypoglycemia Coadministration with these drugs eg, atypical antipsychoticseg, olanzapine and clozapine, corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, lantus solostar efectos secundarios contraceptives, phenothiazines, progestogenseg, oral contraceptives, protease inhibitors, somatropin, sympathomimetic agentseg, albuterol, epinephrine, terbutaline, and thyroid hormones may decrease the risk of hypoglycemia Concomitant use of alcohol, beta-blockers, clonidine, and lithium salts with insulin glargine lantus solostar efectos secundarios increase or decrease blood glucose lowering effect of insulin glargine Pentamidine may cause hypoglycemia, which may sometimes be followed with hyperglycemia Coadministration with beta-blockers, clonidine, guanethidine, or reserpine may blunt signs and symptoms of hypoglycemia Published data do not report a clear association with insulin glargine products and major birth defects, miscarriage, or adverse maternal or fetal outcomes when insulin glargine products used during pregnancy; however, these lantus solostar efectos secundarios cannot definitely establish absence of any risk because of methodological limitations including small sample size and some with no comparative group There are risks to lantus solostar efectos secundarios and fetus associated with poorly controlled diabetes in pregnancy; poorly controlled diabetes in pregnancy increases maternal risk for diabetic ketoacidosis, pre-eclampsia, spontaneous abortions, preterm delivery, lantus solostar efectos secundarios and delivery complications In animal reproduction studies, rats and rabbits were exposed to insulin glargine in animal reproduction studies during organogenesis, respectively 50 times and 10 times the human subcutaneous dose of 0. 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Do not transfer the insulin from the pen into a syringe. Never share an injection pen or syringe with another person, even if the needle has been changed.tml Swinnen SG, Simon ACR, Holleman F, et al.

Insulin detemir versus insulin glargine for type 2 diabetes mellitus.

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Do not dilute or mix Lantus with any other insulin or solution.Using insulin with these drugs may increase this risk. If you also take one of these drugs, talk with the doctor.

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severe allergic reaction whole body reaction Get medical help right away if you have any of these signs or symptoms of a severe allergic reaction: a rash over your whole body, trouble breathing, a fast heartbeat, or sweating.

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Before first use, the pre-filled pen must be stored at room temperature for 1 to 2 hours.o NOT reuse needles.

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If changing patients from once-daily NPH insulin to once-daily LANTUS, the recommended initial LANTUS dose is the same as the dose of NPH that is being discontinued.Let s take a closer look at what happens while injecting using this clear injection dome.

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