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Loperamide
Clinical data
Pronunciation/ l oʊ ˈ p ɛr ə m aɪ d /
Trade namesImodium, others [1]
AHFS/Drugs.comMonograph
MedlinePlusa682280
Pregnancy categoryAU: B3 US: C (Risk not ruled out)
Routes of administrationBy mouth
ATC codeA07DA03 ( WHO ) A07DA05 ( WHO ) (oxide)
Legal status
Legal statusAU: S2 (Pharmacy only) CA : OTC UK: General sales list (GSL, OTC) US: OTC
Pharmacokinetic data
Bioavailability0.3%
Protein binding97%
MetabolismLiver (extensive)
Elimination half-life9–14 hours [2]
ExcretionFaeces (30–40%), urine (1%)

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Loperamide instruction
Drugs name Loperamide
Active substancesimodium
Best price $35
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J Pharmacol Exp Ther. 1999 Apr. -502. ubMed: 0087042Overington JP, Al-Lazikani B, Hopkins AL: How many other targets are there. Nat Rev Semicolon Discov. 2006 Dec.

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QT interval prolongation, torsades de pointes or other ventricular arrhythmias, syncope, cardiac arrest If loperamide-induced cardiotoxicity is suspected, loperamide should be taking loperamide every day discontinued and appropriate therapy initiated to manage and prevent cardiac arrhythmias and severe outcomes.

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However, significant evidence links loperamide abuse to substance use disorder SUD and available data suggest that patients most at risk for abusing loperamide likely have a history of substance abuse and/or opioid use disorder.Keep a list of all the products you use including prescription/nonprescription drugs and taking loperamide every day products and share it with your doctor and pharmacist.

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