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XALATAN should be used with caution in patients with a history latanoprost gotas oftalmicas intraocular inflammation iritis/uveitis and should generally not be used in patients with active intraocular inflammation. Macular edema, including cystoid macular edema, has been reported during treatment with XALATAN. HCPCS 2019 Index - CMS Additional mutagenicity studies on in vitro/in vivo unscheduled DNA synthesis in rats were negative and indicate that latanoprost does not have mutagenic potency.

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The dose should not exceed one drop in the affected ey s daily as more frequent administration may lessen the intraocular pressure lowering effect. Reduction of the intraocular pressure starts approximately 2 to 4 hours after the first administration with the maximum effect reached after 12 hours.If you have asthma, discuss with your doctor how latanoprost may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.

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