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|Pronunciation||/ m ɛ t ˈ f ɔːr m ɪ n /, met- FOR -min|
|Trade names||Glucophage, other|
|License data||EU EMA: by INN, US FDA: metformin|
|Pregnancy category||AU: C US: B (No risk in non-human studies)|
|Routes of administration||by mouth|
|ATC code||A10BA02 ( WHO )|
|Legal status||AU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only|
|Bioavailability||50–60%  |
|Protein binding||Minimal |
|Metabolism||Not by liver |
|Elimination half-life||4–8.7 hours |
|Excretion||Urine (90%) |
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Wing RR, Lang W, Wadden TA, Safford M, Knowler WC, Bertoni AG, et al. Grants of modest metformin hydrochloride tablet 500 mg side in administering full realization screams in streptococcal and obese mice with soluble 2 diabetes. Tubing Glass. 2011 Jul and alternative meds to metformin buy online canada. 1-6.
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Edroxyprogesterone belongs to the family of medications known as progestins.It described research by its founders, which include Harvard's Amy Wagers and Richard Lee, as demonstrating that replenishing a single circulating factor, GDF11, in old animals mirrors the effects of young blood, repairing the heart, brain, metformin hydrochloride 500mg and other tissues.
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Metformin has been used as an metformin hcl 500 mg tab to insulin to reduce insulin requirements in a limited number of patients with type 1 diabetes mellitus, but the potential benefits and risks require further evaluation before such combined therapy can be recommended.Diabetes Zhou G, Myers R, Li Y, Chen Y, Shen X, Fenyk-Melody J, Wu M, Ventre J, Doebber T, Fujii N, Musi N, Hirshman MF, Goodyear LJ, Moller DE 2001 Role of AMP-activated protein kinase in mechanism of metformin action.
J Clin Invest UK Prospective Diabetes Study UKPDS Group 1998 Effect ofintensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes UKPDS 34 UK Prospective Diabetes Study UKPDS Group.
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