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Clinical data
Pronunciation/ m ɛ t ˈ f ɔːr m ɪ n /, met- FOR -min
Trade namesGlucophage, other
License dataEU  EMA:  by INN, US   FDA: metformin
Pregnancy categoryAU: C US: B (No risk in non-human studies)
Routes of administrationby mouth
ATC codeA10BA02 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability50–60% [2] [3]
Protein bindingMinimal [2]
MetabolismNot by liver [2]
Elimination half-life4–8.7 hours [2]
ExcretionUrine (90%) [2]

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Tablets name Metformin
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    J Clin Invest UK Prospective Diabetes Study UKPDS Group 1998 Effect ofintensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes UKPDS 34 UK Prospective Diabetes Study UKPDS Group.

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