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It is a specific inhibitor of the acid pump in the parietal cell.J Clin Pharm Ther. 171-177.

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In a multicenter, double-blind study, endoscopically documented remission of esophagitis was maintained at 6 zantac protectors gastrico in 70, 34, or 11% of patients receiving omeprazole 20 mg daily, 20 mg on 3 consecutive days each week, or placebo, respectively.

In another multicenter, double-blind study in zantac protectors gastrico with endoscopically confirmed healed esophagitis, endoscopic zantac protector gastrico of esophagitis was maintained at 12 months in 77, 58, or 46% of patients receiving omeprazole 20 mg daily, 10 mg daily, or ranitidine 150 mg twice daily, respectively.Monitoring phenytoin plasma concentration is recommended during the first two weeks after initiating omeprazole treatment and, if a phenytoin dose adjustment is made, monitoring and a further dose adjustment should occur upon ending omeprazole treatment.

Concomitant administration of omeprazole with saquinavir/ritonavir resulted in increased plasma levels up to approximately 70% for saquinavir associated with good tolerability in HIV-infected patients.

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Doi.-fold increased risk for developing pneumonia compared with those who discontinued gastric acid suppressants. Such a dose-response relationship for developing pneumonia was not observed in patients receiving H2-receptor antagonists; however, dose variation of these drugs was limited.

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