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2015 Mar; 3 269-92. doi.Edematous states in which secondary aldosteronism is usually involved include congestive heart failure, hepatic cirrhosis, and nephrotic syndrome.
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Bellot P, Welker MW, Soriano G, et al.By several indices other than the primary outcome measures the patients from the West showed the utility of addition of low-dose spironolactone.
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Generation 4 MRAs, aimed at being renal tubule-sparing to minimize hyperkalemia in heart failure, are probably in fact dangerous in PA: hypokalemia is more life-threatening than hyperkalemia.
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