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It increases the permeability of the bacterial cell membrane by interacting pyrimethamine trimethoprim the phospholipid components of the membrane.Observations of leukocytes obtained from patients treated pyrimethamine trimethoprim sulfamethoxazole and trimethoprim revealed no chromosomal abnormalities.

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J Pediatr.So, no more Bactrim for me.

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It is a sulfonamide and bacteriostatic.

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